About 1 result found for searched term "SPL-707 " (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29338 | SPL-707 | Gamma-secretase/Beta-secretase |
| SPL-707 is an orally active, selective signal peptide peptidase-like 2a (SPPL2a) inhibitor with an IC50 of 77 nM for hSPPL2a. SPL-707 inhibits γ-secretase (IC50=6.1 μM) and SPP (IC50=3.7 μM). SPL-707 has the potential for autoimmune diseases research by targeting B cells and dendritic cells. | ||
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